Characterization of Staphylococcus aureus ST3320 clone causing fatal respiratory infection in rabbits

<em>Staphylococcus aureus</em> is a well-known pathogen that infects humans and animals. However, information on the fatal respiratory infection in rabbits caused by<em> S. still limited. In present study, <em>S. isolate designated ND01 was recovered from lung samples of died infection, characterised by intranasal rabbits, multi-locus sequencing typing, screening virulence genes testing antimicrobial susceptibility. Clinical signs matted forepaws pathological lesions haemorrhagic tracheitis necrotising pneumonia were observed infected which identical to those naturally ones. The sequence type defined as ST3320 further grouped into clonal complex 398. Notably, <em>pvl-positive</em> carried human-associated scn gene. Moreover, methicillin-susceptible susceptible 6 10 tested antibiotics. This study described characteristics causing rabbits. results are helpful understanding pathogenicity aureus clone also highlighted operators must be alert for colonisation potential transmission events between humans.